Welcome to the Rh- Medicine & Research Page

A life-saving method of converting blood from one group to another is being attempted by scientists. If successful, it could potentially mean an end to O-Negative blood shortages around the world.

 

Read the Full Article >  Click Here

 

Read the Full Article >  Click Here


Read the Full Article >  Click Here


 

     D.A.R.P.A. & the Arteriocyte's Blood Pharming Program.

 

Scientists at the bioengineering company Arteriocyte had a DARPA contract (Defense and Research Projects Agency) to engineer red blood cells, a process called pharming.

 

Arteriocyte's Blood Pharming program is currently working to combine multiple state of the art technologies to produce fresh units of universal-donor (Type O, RH factor negative) packed red blood cells. The company's proprietary NANEX technology permits 250-fold expansion of hematopoietic stem cells that are subsequently cultured in a unique environment of nutrients and growth factor to induce differentiation into enucleated red blood cells.

 

         Read the Full Article > Click Here

 

         Arteriocyte Link >>>>  Click Here

 

         D.A.R.P.A. Link >>>>  Click Here

 

         Nanex Technology >  Click Here

 

 

Rh- Blood Related US Patents

US Patent 5993812 - Method of delaying the progression of an infection with the human immunodeficiency virus (HIV)

 

Do you have it?

What does it mean?

 

The HLA-B27 Genetic Marker is said to have protective properties that guard against the progression of HIV.  It is said, that people with this gene do not have the right proteins The HLA-B27 Genetic Marker...do you have it? for the HIV virus to bind with. The HLA - B27 Marker is most often found in people with O- Blood.

 

HLA-B27  is an inherited gene marker that is associated with a number of related rheumatic diseases. They share in common, certain features like spinal and peripheral arthritis, skin and GI disorders, anterior chamber eye disease, psoriasis like skin lesions, as well as inflammation and joint pain. This gene is found with highest prevalence in patients with ankylosing spondylosis, reactive arthritis, and patients with the combination of peripheral arthritis and either psoriasis or inflammatory bowel disease To learn more about Ankylosing Spondylitis, click here.

 

Related AS Research Links :

http://en.wikipedia.org/wiki/HLA-B

US Patent 5993812

Journal of Virology

http://arthritis.about.com/od/arthqa/f/HLAB27.htm

Ankylosing Spondylitis

http://www.spondylitis.org/about/faq.aspx

http://www.answers.com/topic/hla-b27

 

Join the NEW Ankylosing Spondylosis Support Forum.

 

 

Rh- Medical Advancements

Ultrasound Detects Rh-Disease Complication in Womb ~ Read Article Here.

 

A new chapter in Rh research: Rh proteins are ammonium transporters ~ Read Article Here.

 

 

Rh Negative? Join the Registry and know where to find others! Click here, only $1.99! 

 

 

Did you know?

 

of the Rh-Neg Blood Group System

 Download Full Article Here 

Rh- Pregnancy?  Be aware of Jaundice and the connection to Cerebral Palsy. Click here to find out more & learn what signs to look for. 

 

Thank You Mr. Harrison!

While many people donate blood and plasma to save lives everyday, James Harrison has a very special type of blood, that he's donated over 900 times and saved the lives of over two million babies. 

His rare genetic gift is an antibody in his blood plasma that can help save babies who suffer from an often fatal form of anemia called Rhesus disease. 

Please click here to read the full article.


 ..
Why Rh-Negative Research?
Read more about why it matters
Two Rh+ people CAN have an Rh- baby if BOTH parents carry the RECESSIVE Rh-Negative Factor!
Two Rh+ people CAN have an
Rh- baby if BOTH parents carry the
RECESSIVE Rh-Negative Factor!


Fingerprints & Blood Types


Interesting study of the ABO Rh
Distribution in Fingerprint patterns.

View & Print Study

Rh- Research Studies with Findings

Rh Negative (Rh-) Blood Studies and Research Findings. 

 

  • STUDY: Epidemiologic evidence linking ABO and Rh blood groups in the mother with neural tube defect lesion level in the child.

Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1716804/ 

 

  • STUDY: A new chapter in Rh research: Rh proteins are ammonium transporters.

Link: http://www.cell.com/trends/molecular-medicine/abstract/S1471-4914(01)01949-9

 

  • STUDY: Rh Incompatibility May Be Schizophrenia Risk Factor.

Link:  http://pn.psychiatryonline.org/content/37/24/21.1.full

Link: http://www.schizophrenia.com/prevention/rhcompat.html 

 

  • STUDY: Rhesus Positivity and Low High-Density Lipoprotein Cholesterol: A New Link?  Rh+ individuals may be predisposed to Coronary Artery Disease(CAD).

Link: http://asianannals.ctsnetjournals.org/cgi/content/full/14/2/119

 

  • STUDY: Carriage rate of Human Immunodeficiency Virus (HIV) infection among different  ABO and Rhesus blood groups in Adamawa state, Nigeria.

Link: http://www.indmedica.com/journals.php?journalid=12&issueid=109&articleid=1496&action=article 

 

  • STUDY: Distribution of ABO and Rh blood groups in patients with HELLP syndrome.

Link: http://www.springerlink.com/content/1k8yda394xme09t8/ 

 

  • STUDY: Breast cancer incidence in Greek women in relation to ABO blood groups and Rh factor.

Link: http://www.issoonline.com/content/6/1/14 

 
Rh- Research Studies ~ Inconclusive

 

  • STUDY: Effects of ABO/Rh Blood groups, G-6-P-D enzyme activity and haemoglobin    genotypes on malaria parasitaemia and parasite density.

Link: http://ajol.info/index.php/ajhs/article/viewFile/30786/23119

 

 

  • STUDY: ABO and Rh blood groups distribution in patients with endometriosis

Link: http://www.springerlink.com/content/br8k272336335612/ 

 

 

  • STUDY: First trimester screening for Down syndrome in rhesus negative women

Link: http://www3.interscience.wiley.com/journal/117926076/abstract?CRETRY=1&SRETRY=0

 

 

  • STUDY: The effect of ABO-Rh blood group determinants on urinary tract infections.

Link: https://www.researchgate.net/publication/6535561_The_effect_of_ABO-Rh_blood_group_determinants_on_urinary_tract_infections 

 

 

Ankylosing Spondylitis or "AS" is an autoimmune disease that may be more prevelant to those people who are tested positive for a genetic marker called HLA-B27.  This theory is based on the research that 85+% of individuals diagnosed with Ankylosing Spondylitis or "AS"; happen to test positive for the HLA-B27 genetic marker, which is said to be had by only about 8% of the population or less, based on geographical location.  I saw a connection because the blood type O- also appears in about 7% of the population and again that percentage varies by the geographical location of the population.  After researching this connection and family history, I felt confidant enough to lay out my theory for my mothers' doctors, they listened and tested her for the genetic marker and it came back positive. 

 

I do not know what the connection is; but I am looking, researching and trying to find the answers.  In the meantime, I am learning about symptoms, treatments, effects and more.  I will share with you what I find. Together, hopefully we can find the answers to improve the human condition. Click the links below, find out more or join the forum.

 


The Ankylosing Splondylitis Forum

Ankylosing Splondylitis Research & Resources

 

 

Free Download or Printable Daily Pain Log. Click Here!



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Rh Factor & Sexual Orientation
Eye color, hair color, blood type, and the rhesus factor:
Exploring possible genetic links to sexual orientation.

Source: Department of Sociology, Minot State University, Minot, ND 58707, USA.
Email ~  http://www.ncbi.nlm.nih.gov/pubmed/18074215 ~ Ellis L, Ficek C, Burke D, Das S.

The present study sought to expand the limited evidence that sexual orientation is influenced by genetic factors. This was accomplished by seeking statistical differences between heterosexuals and homosexuals for four traits that are known to be genetically determined: eye color, natural hair color, blood type, and the Rhesus factor. Using a sample of over 7,000 U.S. and Canadian college students supplemented with additional homosexual subjects obtained through internet contacts, we found no significant differences between heterosexuals and homosexuals regarding eye color or hair color. In the case of blood type and the Rh factor, however, interesting patterns emerged. Heterosexual males and females exhibited statistically identical frequencies of the A blood type, while gay men exhibited a relatively low incidence and lesbians had a relatively high incidence (p < .05). In the case of the Rh factor, unusually high proportions of homosexuals of both sexes were Rh- when compared to heterosexuals (p < .06). The findings suggest that a connection may exist between sexual orientation and genes both on chromosome 9 (where blood type is determined) and on chromosome 1 (where the Rh factor is regulated).

 
What is Bombay Blood?
 It can be difficult to predict the ABO blood type of children based on the phenotypes of their parents, due to the fact that a third antigen (H) on the surface of red cells can prevent the expected ABO blood type options from occurring. 


Usually, when an A blood type mother has an O type child, the father is expected to be type O or at least to carry the O allele recessively (OO, AO, or BO genotype).

Phenotypes vs Genotypes and Type O's!
The child has inherited an O allele from both parents.  However, an O blood type child can also be born to parents who do not have the O allele if a recessive form of the allele for the H antigen also is inherited from both parents.
Phenotypes vs Genotypes and Type O's!
The H antigen is a precursor to the A and B antigens.  For instance, the B allele must be present to produce the B enzyme that modifies the H antigen to become the B antigen. As well, the A allele must be present to produce the A enzyme that modifies the H antigen to become the A antigen.  

However, when only recessive alleles for the H antigen are inherited (hh), as in the case above, the H antigen will not be produced and thus, the A and B antigens will not be produced either .  The result is an O phenotype, by default since a lack of A and B antigens is the O type.  This seemingly impossible phenotype result has been referred to as a Bombay phenotype. 

The ABO blood system is further complicated by the fact that there are two subtypes of type A and two subtypes of type AB.  These are A1,  A2,  A1B,  and A2B.